Thursday, April 9, 2015

Best Drugs Used During Pregnancy

                     Pregnancy, also known as gravidity or gestation, is the time during which one or more offspring develops inside a woman. It usually last around 40 weeks (10 lunar months) from the last menstrual period (LMP) and ends in childbirth.

Pregnancy is typically divided into Three Trimesters.
1. First trimester
The first trimester is from week one to twelve and includes conception. Conception is followed by the fertilized egg traveling down the fallopian tube and attaching to the inside of the uterus where it begins to form the fetus and placenta. The first trimester carries the highest risk of miscarriage (natural death of embryo or fetus).
2. Second trimester
The second trimester is from week 13 to 28. Around the middle of the second trimester movement of the fetus may be felt. At 28 weeks more than 90% of babies can survive outside of the uterus if provided high quality medical care.
3. Third trimester
The third trimester is from 29 weeks to 40 weeks. Final weight gain takes place, which is the most weight gain throughout the pregnancy. The woman's abdomen will transform in shape as it drops due to the fetus turning in a downward position ready for birth.



Drugs used during pregnancy can have temporary or permanent effects on the fetus. Therefore many physicians would prefer not to prescribe for pregnant women, the major concern being over teratogenicity of the drugs. The best drugs used during pregnancy are :

 For Hypertension 
- Alpha methyl dopa (250mg tab)

 For Hyperthyroidism
- Propylthiouracil ( 50mg tab )

 For Hyperacidity
- Magalderate - AL & Mg Hydroxide - may need of use ....Ranitidine as second line

 For Diabetes
- Intermediate acting insulin ( Humulin 30/70 )

 For Thrombosis
- Heparin or Low _molecular Heparin

 For Vomiting
1. First Line : Pyridoxine (vitamin B6 )+ meclozine Hcl DOSE: ( 25MG pyridoxine / 12.5 mg Meclozine Hcl ….orally 3 times daily )
2. Second Line : Metoclopramide DOSE : -( 5-10mg ) orally three to four times daily OR  Chlorophenoxamine Dose : ( I tab) three times daily OR Diphenylhydramine Dose : 1 tab (2-3) times daily
3. Third Line : In case of Hyperemesis Ondansetron.

 For Fever
- Paracetamol

 For Diarrhea
- Nifuroxazide

 For Constipation
- Sod. Picosulphate - Lactulose

 For Cough
- Mix of natural Plant Extracts

 For Bronchospasm
- Terbutaline

 For Intestinal Spasm
- Drotaverine (80mg)


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