Magnesium is a naturally occurring mineral that is important for many systems in the body especially the muscles and nerves. Magnesium sulfate injection is used to treat hypomagnesemia (low levels of magnesium in your blood). Magnesium sulfate injection is also used to prevent seizures in pregnant women with conditions such as pre-eclampsia, eclampsia, or toxemia of pregnancy.
Tell your doctor if you drink alcohol or caffeine drinks regularly, if you smoke, or if you use any street drugs. These factors can affect the way magnesium sulfate injection works in your body.
Side Effects
1. Allergy
2. Hives
3. Difficult breathing
4. Swelling of your face, lips, tongue, or throat.
5. Sweating, anxiety, cold feeling
6. Extreme drowsiness, feeling very weak
7. Numbness or tingly feeling around your mouth, muscle tightness or contraction, overactive reflexes.
Dose
1. Usual Adult Dose for Hypomagnesemia:
1 g IM every 6 hours for 4 doses (mild hypomagnesemia) or
as much as 2 mEq/kg (0.5 mL of a 50% solution) within 4 hours if necessary (more severe hypomagnesemia) or
5 g in 1 L IV fluid over 3 hours.
Administration should be discontinued as soon as the desired clinical effect is achieved and the serum level is normal.
2. Usual Adult Dose for Ventricular Arrhythmia:
Initial dose: 1 to 3 g IV bolus over 2 to 15 minutes.
Most studies have continued infusions for 24 to 48 hours.
A 1 to 3 g bolus may be repeated in 15 minutes.
Thereafter, 1 to 2 g may be administered by continuous IV infusion.
3. Usual Adult Dose for Seizure Prophylaxis:
Seizure Prevention in Preeclampsia/Eclampsia:
Initial: IM: 4 to 5 g of a 50% solution every 4 hours as necessary.
IV: 4 g of a 10% to 20% solution, not exceeding 1.5 mL/min of a 10% solution.
Maintenance: IV Infusion: 1 to 2 g/hour. Maximum dose should not exceed 30 to 40 g/day.
Duration: Continuous administration beyond 5 to 7 days can cause fetal harm.
Contraindications
Parenteral administration of the drug is contraindicated in patients with heart block or myocardial damage.
Tell your doctor if you drink alcohol or caffeine drinks regularly, if you smoke, or if you use any street drugs. These factors can affect the way magnesium sulfate injection works in your body.
Side Effects
1. Allergy
2. Hives
3. Difficult breathing
4. Swelling of your face, lips, tongue, or throat.
5. Sweating, anxiety, cold feeling
6. Extreme drowsiness, feeling very weak
7. Numbness or tingly feeling around your mouth, muscle tightness or contraction, overactive reflexes.
Dose
1. Usual Adult Dose for Hypomagnesemia:
1 g IM every 6 hours for 4 doses (mild hypomagnesemia) or
as much as 2 mEq/kg (0.5 mL of a 50% solution) within 4 hours if necessary (more severe hypomagnesemia) or
5 g in 1 L IV fluid over 3 hours.
Administration should be discontinued as soon as the desired clinical effect is achieved and the serum level is normal.
2. Usual Adult Dose for Ventricular Arrhythmia:
Initial dose: 1 to 3 g IV bolus over 2 to 15 minutes.
Most studies have continued infusions for 24 to 48 hours.
A 1 to 3 g bolus may be repeated in 15 minutes.
Thereafter, 1 to 2 g may be administered by continuous IV infusion.
3. Usual Adult Dose for Seizure Prophylaxis:
Seizure Prevention in Preeclampsia/Eclampsia:
Initial: IM: 4 to 5 g of a 50% solution every 4 hours as necessary.
IV: 4 g of a 10% to 20% solution, not exceeding 1.5 mL/min of a 10% solution.
Maintenance: IV Infusion: 1 to 2 g/hour. Maximum dose should not exceed 30 to 40 g/day.
Duration: Continuous administration beyond 5 to 7 days can cause fetal harm.
Contraindications
Parenteral administration of the drug is contraindicated in patients with heart block or myocardial damage.
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