Causes of Hepatomegaly

      Hepatomegaly is the condition of having an enlarged liver. It is a nonspecific medical sign having many causes, which can broadly be broken down into infection, direct toxicity, hepatic tumours, or metabolic disorder.

Common Causes of Hepatomegaly are :
1. Infective
- Glandular fever (Infectious mononucleosis)
- Hepatitis (Although not all hepatitis viruses cause hepatomegaly)
- Liver abscess (pyogenic abscess and amoebic abscess)
- Malaria
- Amoeba infections
- Hydatid cyst
- Actinomycosis
2. Neoplastic
- Metastatic tumours secondary to spread from cancer in other organs (most common)
- Hemangiomas
- Hepatocellular carcinoma
- Myeloma
- Leukemia
- Lymphoma
3. Cirrhotic
- Portal
- Biliary
- Cardio
- Haemochromatosis
4. Metabolic 
- Fatty infiltration
- Gaucher's disease
- Glycogen Storage Disease types III, VI and IX
5. Drugs and toxins
- Alcoholism
- Poisoning
6. Congenital 
- Hemolytic anemia
- Polycystic disease
- Cori's disease
7. Others 
- Budd–Chiari syndrome
- Hunter syndrome
- Zellweger's syndrome
- Right ventricular failure
- Glycogen storage disease type II

Hepatomegaly